"I've even said to Jason, 'I will jump off a building for you, but I will not do that," she said.
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Theron also revealed that she had turned down offers from director Jason Reuitman to be part of his famous theatrical reading at Los Angeles's County Museum of Arts because she could not handle the stress.
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"I think maybe that's the difference between acting and being a performer... As soon as there are 200 people in a theatre watching me, I get really scared," she added.
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"I'm just not made for that kind of live audience where you don't create a fourth wall. I take my hat off to those guys. It's not disconnected enough for me... Some people are good at performing in front of people like that, but I'm uncomfortable at it," she said.
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Earlier, Charlize said that she cannot do theatre as she is unable to handle live audience.
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She will pose in lingerie with her Prometheus co-star Michael Fassbender.
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The actor will soon be seen in one of her raciest photo shoots ever in the August issue of W magazine.
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"It depends on who you're doing the sex scene with. I don't have issues being naked. What I mean is, I'm not hung up on my body, and I've been lucky to work with people I've been really comfortable with. I've had maybe two occasions where it's been uncomfortable," she said.
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The 36 year old, who has stripped off in films like 2 Days in the Valley, The Devils Advocate and Young Adult, said a lot of it depends on the comfort level with the co-star and she has been lucky to have worked with all known people.
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Monster star Charlize Theron says she is comfortable doing intimate scenes on-screen and does not have any inhibitions as an actor.
